Regenerative Care · Exo-W / Exo-D

Human stem cell conditioned media.

Derived from umbilical cord Wharton's Jelly, dental pulp, and adipose tissue. The exosome platform behind every Hakke formulation.

What are exosomes?

Exosomes are microscopic vesicles secreted by stem cells, studied for their role in cellular communication and self-regeneration. They are of interest in skin renewal and hair restoration research.

Derived from human stem cell conditioned media, exosomes carry growth factors, peptides, and other bioactive molecules that work together to support the body's own repair processes at the cellular level. Hakke's role is to isolate, quantify, and manufacture that signalling cargo to a consistent, documented standard.

Where exosomes come from.

The exosomes used across Hakke's formulations are collected from stem cells cultured from three tissue sources, each obtained from ethically sourced donors under strict laboratory conditions.

Wharton's Jelly
Umbilical cord
Collected from the umbilical cord of healthy, full-term newborns. The primary source behind Exo-W and the Revival Serum line.
Dental Pulp
Reference tissue
A comparison tissue used to characterise how signalling profiles differ by source, informing which formulation suits which application.
Adipose Tissue
Fat-derived
Collected from ethically sourced donors as a third reference point in Hakke's ongoing tissue-origin research.

Cellular messengers, not cells themselves.

Exosomes carry signalling cargo from a donor cell to a recipient cell. Repair instructions, not living tissue. That distinction is the entire premise of what Hakke manufactures.

Donor cell Exosomes Signalling cargo Recipient cell
Signal transfer from donor cell to recipient cell, mediated entirely by extracellular vesicles.Fig. 01

Signalling molecules of interest.

Growth factors most closely associated with the regenerative signalling pathways Hakke's formulations are designed around.

HGF
Hepatocyte Growth Factor
IGF-1
Insulin-Like Growth Factor
EGF
Epidermal Growth Factor
KGF
Keratinocyte Growth Factor
TGF-β
Transforming Growth Factor Beta
PDGF
Platelet-Derived Growth Factor
Hakke's quantified bioactive profile, including measured pg/mL concentrations by marker, is available in the clinical documentation provided to practitioners. Descriptions here are mechanism-based and are not claims of guaranteed clinical outcome.

Harness the power of regeneration.

To learn more about exosome technology and how Hakke applies it across skin and scalp protocols, get in touch with our team.